Cupola of the Duomo Di San Gennaro, Naples, Italy illustrating a heavenly scene..San Gennaro is the patron saint of Naples. He was a Bishop from Benevento (Campania, near Naples), and was beheaded in 305AD. His relics are kept in the Duomo of San Gennaro in Naples, including 2 vials of dried blood. Three times per year, thousands of Neapolitans and tourists from all over Italy and the world flock to the Duomo to witness a miracle: the liquification of his blood, which was first recorded in 1389